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Robert D. Terry, M.D. Professor Emeritus, Departments of Pathology and Neurosciences Email: rterry@ucsd.edu
Education: Williams College, Williamstown MA B.A. 1946 Chemistry
Albany Medical College of Union M.D. 1950 Medicine
University, Albany NY
Professional Experience:
7/50-12/50 St. Francis Hospital, Hartford, CT, Dept. of Pathology, Assist. Resident
1/51-12/51 Bellevue Hospital, New York, NY, 1st Div. (Columbia Univ.), Surgery & Medicine, Intern
Montefiore Hospital and Medical Center, Bronx, New York
1/52-6/53 Dept. of Pathology, Assist. Resident, and Resident
7/54-6/55 Post-Doctoral Fellow (NIHD)
1955-59 Assist. Neuropathologist Institut de recherches sur le Cancer, Paris, France
7/53-6/54 Stagiare de Recherche, (Prof. C. Oberling).
1965-66 Senior Post-Doctoral Fellow (National Science Foundation)
Albert Einstein College of Medicine, Dept. of Pathology, Bronx, NY
1959-64 Associate Professor (Neuropathology)
1964-84 Professor (Neuropathology)
1970-84 Chairman (Acting Chairman, 1969)
1974-84 Department of Neurosciences, Professor
1959 Bronx Municipal Medical Center, Bronx, NY, Pathology/Neuropathology attending
1966-84 Albert Einstein College of Medicine Hospital, Bronx, NY, Pathology/Neuropathology attending
2/73 Institute of Neurology, The National Hospital, Queen Square, London, England, Visiting Professor
University of California, San Diego
1984-94 Professor of Neurosciences and of Pathology
1994-present Professor Emeritus of Neurosciences and of Pathology
1955 Diplomate, American Board of Pathology (Anatomic Pathology
1962 Diplomate, American Board of Pathology (Neuropathology)
1988 Potamkin Prize for Research on Alzheimer's Disease,
1989 Distinguished Service Award-American Association of Neuropathologists
1991 Metropolitan Life Foundation Award
1991 D.Sc. (Honorary) - Williams College
PUBLICATIONS (selected):
Link to PUB MED Search Results
1. Terry, R.D., Gonatas, N.K., Weiss, M. Ultrastructural studies in Alzheimer's presenile dementia. The American Journal of Pathology 44:269-297, 1964.
2. Davies, P., Katzman, R., Terry, R.D. Reduced somatostatin-like immunoreactivity in cerebral cortex from cases of Alzheimer disease and Alzheimer senile dementia. Nature (London) 288:279-280, 1980.
3. Terry, R.D., Peck, A., DeTeresa, R., Schechter, R., Horoupian, D.S. Some morphometric aspects of the bain in senile dementia of the Alzheimer type. Annals of Neurology 10:184-192, 1981.
4. Terry, R.D., DeTeresa, R., Hansen, L.A. Neocortical cell counts in normal human adult aging. Annals of Neurology 21:530-539, 1987.
5. Terry, R.D., Hansen, L.A., DeTeresa, R., Davies, P., Tobias, H., Katzman, R. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. Journal of Neuropathology and Experimental Neurology 46:262-268, 1987.
6. Masliah, E., Terry, R., Buzsaki, G. Thalamic nuclei in Alzheimer disease: Evidence against the cholinergic hypothesis of plaque formation. Brain Research 493:240-246, 1989.
7. Masliah, E., Terry, R.D., DeTeresa, R.M., , Hansen, L.A. Immunohistochemical quantification of the synapse-related protein synaptophysin in Alzheimer disease. Neuroscience Letters 103:234-239, 1989.
8. Masliah, E., Terry, R.D., Alford, M., DeTeresa, R. Quantitative immunohistochemistry of synaptophysin in the human neocortex C An alternative method to quantify synapses in paraffin sections. Journal of Histochemistry and Cytochemistry 38:837-844, 1990.
9. Terry, R.D., Masliah, E., Salmon, D.P., Butters, N., DeTeresa, R., Hill, R., Hansen, L.A. Katzman, R. Physical basis of cognitive alterations in Alzheimer disease: Synapse loss is the major correlate of cognitive impairment. Annals of Neurology 30:572-580, 1991.
10. Terry, R.D. The Pathogenesis of Alzheimer's Disease. What Causes Dementia? In: Neurophilosophy and Alzheimer's Disease, (Y. Christen, P. Churchland, eds.), Foundation Ipsen, Springer-Verlag, New York, pp.123-130, 1992.
11. Terry, R.D. Neuronal and synaptic loss in aging and in Alzheimer disease. In: Development and Involution of Neurones, (K. Fujisawa, Y. Morimatsu, eds.), Japan Scientific Societies Press, Tokyo, pp. 219-226, 1992.
12. Terry, R.D. Regeneration in Alzheimer Disease and Aging. In: Advances in Neurology C Neural Injury and Regeneration. Seil, F.J. (ed). Raven Press, New York, volume 59, pp. 104, 1993.
13. Masliah, E., Mallory, M., Hansen, L., DeTeresa, R., Terry, R.D. Quantitative synaptic alterations in the human neocortex during normal aging. Neurology 43:192-197, 1993.
14. Masliah, E., Terry, R. The role of synaptic proteins in the pathogenesis of disorders of the central nervous system. Brain Pathology 3:77-85, 1993.
15. Mirra, S.S., Hart, M.N., Terry, R.D. Making the diagnosis of Alzheimer's disease. Archives of Pathology and Laboratory Medicine 117:132-144, 1993.
16. Hansen, L.A., Masliah, E., Galasko, D., Terry, R.D. Plaque-only Alzheimer disease is usually the Lewy body variant, and vice versa. Journal of Neuropathology and Experimental Neurology 52: 648-654, 1993.
17. Masliah, E., Terry, R.T. The role of synaptic pathology in the mechanisms of dementia in Alzheimer's disease. Clinical Neuroscience 1:192-198, 1993.
18. Samuel, W., Terry, R.D., DeTeresa, R., Butters, N., Masliah, E. Clinical correlates of cortical and nucleus basalis pathology in Alzheimer dementia. Archives of Neurology 51:772-778, 1994.
19. Samuel, W., Masliah, E., Hill, L.R., Butters, N., Terry, R. Hippocampal connectivity and Alzheimer's dementia: Effects of synapse loss and tangle frequency in a two-component model. Neurology 44:2081-2088, 1994.
20. Masliah, E., Honer, W.G., Mallory, M., Voigt, M., Davies, P., Kushner, P., Hansen, L., Terry, R. Topographical distribution of synaptic-associated protein in the neuritic plaques of Alzheimer's disease hippocampus. Acta Neuropathologica 87-135-142, 1994.
21. Alford, M.F., Masliah, E., Hansen, L.A., Terry, R.D. A simple dot-immunobinding assay for quantification of synaptophysin-like immunoreactivity in human brain. The Journal of Histochemistry and Cytochemistry 42:283-287, 1994.
22. Terry, R.D., Katzman, R., Bick, K.L. (eds.) Alzheimer Disease Raven Press: New York, pp.472 pp., 1994.
23. Terry, R.D., Masliah, E., Hansen, L.A. Structural Basis of the Cognitive Alterations in Alzheimer's Disease. In: Alzheimer Disease. Terry, R.D., Katzman, R., Bick, K. (eds.), Raven Press, New York, pp. 179-196, 1994.
24. Masliah, E., Mallory, M., Hansen, L., DeTeresa, R., Alford, M., Terry, R. Synaptic and neuritic alterations during the progression of Alzheimer's disease. Neuroscience Letters 174:67-72, 1994.
25. Terry, R.D. Biologic differences between early- and late-onset Alzheimer disease. Alzheimer Disease and Associated Disorders 9:S26-S27, 1995.
26. Terry, R.D. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. Journal of Neuropathology and Experimental Neurology 55:1023-1025, 1996.
27. Terry RD. The pathogenesis of Alzheimer disease: an alternative to the amyloid hypothesis. J Neuropathol Exp Neurol. 1996 Oct;55(10):1023-5. Review.
28. Terry RD. The pathology of Alzheimer's disease: numbers count. Ann Neurol. 1997 Jan;41(1):7.
29. Hansen LA, Terry RD. Position paper on diagnostic criteria for Alzheimer disease. Neurobiol Aging. 1997 Jul-Aug;18(4 Suppl):S71-3.
30. Terry RD. The cytoskeleton in Alzheimer disease. J Neural Transm Suppl. 1998;53:141-5. Review.
31. Terry RD. Where in the brain does Alzheimer's disease begin? Ann Neurol. 2000 Apr;47(4):421.
32. Terry RD. Cell death or synaptic loss in Alzheimer disease. J Neuropathol Exp Neurol. 2000 Dec;59(12):1118-9.
33. Terry RD. An honorable compromise regarding amyloid in Alzheimer disease. Ann Neurol. 2001 May;49(5):684.
34. Terry RD, Katzman R. Life span and synapses: will there be a primary senile dementia? Neurobiol Aging. 2001 May-Jun;22(3):347-8; discussion 353-4.
35. Terry,R.D.: Tangles precede plaques but don’t cause them. Neurobiology of Aging 25: 741-742, 2004.
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